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Figure 2 | Cell Communication and Signaling

Figure 2

From: Regulation of the actin cytoskeleton in Helicobacter pylori-induced migration and invasive growth of gastric epithelial cells

Figure 2

Model of migrating epithelial cells. For efficient migration, epithelial cells develop new actin-dependent protrusions which are connected to the ECM via newly assembled focal adhesions (red) at the leading edge. Secretion of proteases to degrade ECM is required to extend the protrusion into the ECM to form invadopodia. At the tail, matured focal adhesions (grey) disassemble to facilitate the movement of the cell body in a defined direction.

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Cell Communication and Signaling

ISSN: 1478-811X