Fig. 3

The role of VSIG2 in cell migration and epithelial-mesenchymal transition (EMT) of PDAC. A, B, C, D The migration ability of PANC-1 and AsPC-1 cells with VSIG2 down-regulation and overexpression was identified by evaluating relative migration rate via scratch assay, *P<0.05, **P<0.01. E, F, G, H The levels of EMT after knocking down and up-regulating VSIG2 expression in PANC-1 and AsPC-1 cells were verified by immunoblotting through assessing proteins expression of EMT related indicators including E-cadherin, N-cadherin, Vimentin, and ZEB1, when GAPDH was used as a loading control