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Table 2 International Classification of Retinoblastoma and Prediction of outcomes of surgery

From: Retinoblastoma: present scenario and future challenges

Groups

Criterion

Number of Patients in group based on the study [49]

n = 249

Treatment and success rate

Group A

Retinoblastoma tumor with size <  = 3 mm.

23 (9%)

Chemo reduction with vincristine, etoposide and carboplatin for 6 cycles (CRD) plus thermotherapy or cryotherapy.

100%

Group B

RB tumor with size > 3 mm, has a location close to the macula or presents with small amount of subretinal fluid.

96 (39%)

CRD plus thermotherapy or cryotherapy.

93%

Group C

Eyes with localised seeding of the tumor.

21 (8%)

CRD plus thermotherapy or cryotherapy.

90%

Group D

Diffuse seeding of the tumor within the eyes.

109 (44%)

CRD plus thermotherapy or cryotherapy.

47%

Group E

Huge mass of the tumor covering a great proportion of the eye.

0 as the patients needed management with enucleation and hence were excluded from the study.

Enucleation with CRD in certain cases.