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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML

Fig. 6

O-GlcNAcylation on TWIST1 affect the DAC resistance of MDS clone cells. A The scheme of the xenotransplantation mouse model. B FACS analysis of percentages of hCD45+ cells in peripheral blood. C Overall survival curve of mice injected KG1a-KO-TWIST1-WT or KG1a-KO-TWIST1-mutation. D The xenotransplantation mouse model. E FACS analysis for percentages of KG1a-TWIST1 cells in peripheral blood. F Overall survival curve of mice injected with KG1a cells and treated with DAC ± OSMI-1. **p < 0.01, ns: not significant

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Cell Communication and Signaling

ISSN: 1478-811X