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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Peroxiredoxin II regulates exosome secretion from dermal mesenchymal stem cells through the ISGylation signaling pathway

Fig. 4

Prx II depletion downregulates ISGylation by regulating the STAT signaling pathway. A Western blot analysis of phospho-STAT1, STAT1, phospho-STAT2, STAT2, and IRF9 in Prx II +/+ and Prx II −/− DMSCs. Quantification of phospho-STAT2, STAT2, and IRF9 expression. B mRNA levels of STAT1, STAT2, and IRF9 in Prx II +/+ and Prx II −/− DMSCs were determined using qRT-PCR. *P < 0.05, ***P < 0.001 as determined by two-tailed t test

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Cell Communication and Signaling

ISSN: 1478-811X