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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Transcriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cells

Fig. 3

Time trends in the expression of genes related to TGFβ signaling in MCF10A and MCF7 cells. (a) Genes involved in SMAD-mediated signaling. (b) Transcription factors involved in EMT. (c) Epithelial (CDH1) and mesenchymal markers. The cells were treated according to the scheme shown in Figure S2a. TGF, direct TGFB1 treatment; CM, conditioned medium treatment. *** padj < 0.0001, ** padj < 0.001, * padj < 0.05 (significance of differences was marked for the entire run if the adjusted p value vs. Ctr reached a given value at least at one experimental point). See also Figure S5b

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Cell Communication and Signaling

ISSN: 1478-811X