Fig. 3

Effects of AKG on GSH and NADPH in cumulus cells and oocytes (A) The expressions of target genes in cumulus cells expressed by log2 (TPM + 1), n = 3. (B) The expressions of target genes in oocytes expressed by log2 (TPM + 1), n = 8. (C-E) The levels of GSH, GSSG and GSH/GSSG in cumulus cells and oocytes of COCs, normalized to the content in one oocyte or 104 cumulus cells, n = 3. (F-H) NADPH, NADP+, NADPH /NADP + levels in cumulus cells and oocytes in COCs, normalized to the content in one oocyte or 104 cumulus cells, n = 3