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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis

Fig. 8

Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK Cleavage-Mediated inhibition of macrophage efferocytosis. A A schematic diagram depicting bacterial vesicle-mediated inhibition of macrophage efferocytosis and (B) underlying mechanisms: SAVs inhibit macrophage efferocytosis by modulating the expression of efferocytosis receptor genes through the TLR2-MyD88-NF-κB pathway and induce the cleavage and shedding of Mer tyrosine kinase (MerTK) via the TLR2-MyD88-p38 MAPK pathway

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Cell Communication and Signaling

ISSN: 1478-811X