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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy

Fig. 1

Schematic diagram of glycolysis process. Enzymes: GLUTs (glucose transporter proteins), HK (hexokinase), PGI (phosphoglucose isomerase), PFK-1 (6-phosphofructo-1-kinase), PFK-2 (6-phosphofructo-2-kinase), ALDOA (aldolase A), TPI (triosephosphate isomerase), GAPDH (glyceraldehyde-3-phosphate dehydrogenase), PGK (phosphoglycerate kinase), PGAM (phosphoglycerate mutase), ENO (enolase), PK (pyruvate kinase), LDH (lactate dehydrogenase), MCTs (monocarboxylate transporters). Glycolytic intermediates: G6P (glucose-6-phosphate), F6P (fructose-6-phosphate), F2,6BP (fructose-2,6-bisphosphate), F1,6BP (fructose-1,6-bisphosphate), GA3P (glyceraldehyde-3-phosphate), DHAP (dihydroxyacetone phosphate), 1,3-BPGA (1,3-bisphosphoglycerate), 3-PGA (3-phosphoglycerate), 2-PGA (2-phosphoglycerate), PEP (phosphoenolpyruvate), NADH (nicotinamide adenine dinucleotide reduced form), NAD+ (nicotinamide adenine dinucleotide). Abbreviation: PPP (pentose phosphate pathway), TCA cycle (Krebs cycle), NADPH (nicotinamide adenine dinucleotide phosphate, reduced form), R5P (ribulose-5-phosphate). The overall reaction equation for the glycolysis process was shown

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Cell Communication and Signaling

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