Fig. 6

Regulation of epigenetic modulators (HDAC isoforms) by (A) Galangin, (B) SAHA, and (C) Combination of Galangin and SAHA. Expression changes in epithelial and mesenchymal markers induced by (D) Galangin, (E) SAHA, and (F) A combination of Galangin and SAHA. Modulation of key proteins in the PI3K/AKT/mTOR pathway by (G) Galangin, (H) SAHA, and (I) Combination of Galangin and SAHA