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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: The ester derivative Palmitoylcarnitine abrogates cervical cancer cell survival by enhancing lipotoxicity and mitochondrial dysfunction

Fig. 9

PC increases the cytotoxic effects of cisplatin. A Representative bar graph showing the percentage viability of SiHa and HeLa cells in response to cisplatin and co-exposure with cisplatin and PC (*Compared to untreated (Cis 0.0 μM); #Compared to PC treatment; $Compared to Cisplatin treatment). B Representative Western blot images and bar graph showing the expression of Caspase 9 and Caspase 3 in control, PC-exposed, Cisplatin-exposed, and combined treatment of PC and Cisplatin in SiHa and HeLa cells, respectively. C A representative bar graph shows the percentage viability of SiHa and HeLa cells in response to CCCP and co-exposure to CCCP and PC. Both PC and CCCP exposure induced cell death in SiHa and HeLa cells. However, the combination of CCCP with PC did not significantly increase cell death at the lower doses used in this study. *P < 0.05, **P < 0.01, and ***P < 0.001 indicates statistical significance

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Cell Communication and Signaling

ISSN: 1478-811X